San Francisco at Indianapolis: Point Spread Analysis

Monday Dec 22, 2025 8:15 pm - Indianapolis, IN
Odds: San Francisco by 4, Total Points: 46.5

Matchup Menu: SF @ IND

More Games From Week 16

ATS Predictions

Pick Model Confidence
San Francisco -4.0 Official TR Pick San Francisco 50% odds to cover
San Francisco -4.0 Similar Games San Francisco 64% odds to cover
San Francisco -4.0 Decision Tree San Francisco 51% odds to cover
Indianapolis +4.0 Power Ratings Indianapolis 62% odds to cover
Indianapolis +4.0 Predictive Ratings Indianapolis 69% odds to cover

NOTE: Predictions stop updating roughly 1 hour before game time.

ATS Situational Trends (Last Season)

Record SF adv IND
Season 11-7-1 8-7-2
vs Division 3-4-0 3-3-0
vs Conference 9-5-0 7-4-1
Streak L1 W1
Last 5 3-2-0 2-3-0
Last 10 6-3-1 3-5-2
Home 3-4-1 4-4-0
Away 8-3-0 4-3-2

San Francisco Detailed ATS Performance

Date H/A/N Opponent Line Result +/-
09/10 Away LA Rams +3.5 W by 20 +23.5

Indianapolis Detailed ATS Performance

Date H/A/N Opponent Line Result +/-