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Louisville vs. Indiana: Point Spread Analysis

Saturday Dec 6, 2025 2:15 pm - Indianapolis, IN (Neutral Site)
Odds: Louisville by 4, Total Points: 162.5

Matchup Menu: LOU vs. IND

More Games From Dec 6, 2025

ATS Predictions

Pick Model Confidence
Indiana +3.5 Official TR Pick Indiana 53% odds to cover
Indiana +3.5 Power Rating Model Indiana 57% odds to cover
Indiana +3.5 Similar Games Indiana 58% odds to cover
Indiana +3.5 Decision Tree Indiana 54% odds to cover
Louisville -3.5 Predictive Ratings Louisville 54% odds to cover

ATS Situational Trends

Record LOU adv IND
Season 17-18-0 14-18-0
vs Division 0-0-0 0-0-0
vs Conference 7-13-0 9-12-0
Streak L1 L2
Last 5 2-3-0 1-4-0
Last 10 3-7-0 2-8-0
Home 10-7-0 9-9-0
Away 7-11-0 5-9-0

Louisville Detailed ATS Performance

Date H/A/N Opponent Line Result +/-
11/03 Home S Carolina St -36.5 W by 59 +22.5
11/06 Home Jackson St -38.5 W by 36 -2.5
11/11 Home Kentucky -6.0 W by 8 +2.0
11/15 Home Ohio -31.0 W by 25 -6.0
11/21 Neutral Cincinnati -8.5 W by 10 +1.5
11/24 Home E Michigan -33.5 W by 41 +7.5
11/26 Home NJIT -43.5 W by 57 +13.5
12/03 Away Arkansas -2.0 L by 9 -11.0
12/06 Neutral Indiana -4.0 W by 9 +5.0
12/13 Home Memphis -16.5 W by 26 +9.5
12/16 Away Tennessee +4.5 L by 21 -16.5
12/20 Home Montana -30.5 W by 40 +9.5
12/30 Away California -7.5 W by 20 +12.5
01/02 Away Stanford -7.0 L by 4 -11.0
01/06 Home Duke (Pick) L by 11 -11.0
01/10 Home Boston College -21.0 W by 13 -8.0
01/13 Home Virginia -4.5 L by 9 -13.5
01/17 Away Pittsburgh -7.0 W by 41 +34.0
01/24 Home Virginia Tech -13.5 W by 14 +0.5
01/26 Away Duke +8.5 L by 31 -22.5
01/31 Home SMU -9.5 W by 14 +4.5
02/04 Home Notre Dame -18.0 W by 11 -7.0
02/07 Away Wake Forest -9.5 W by 8 -1.5
02/09 Home NC State -7.5 W by 41 +33.5
02/14 Neutral Baylor -7.0 W by 11 +4.0
02/17 Away SMU -4.0 L by 10 -14.0
02/21 Home Georgia Tech -23.0 W by 17 -6.0
02/23 Away North Carolina -3.5 L by 3 -6.5
02/28 Away Clemson -2.5 L by 5 -7.5
03/03 Home Syracuse -14.5 W by 15 +0.5
03/07 Away Miami +1.5 W by 3 +4.5
03/11 Neutral SMU -6.5 W by 4 -2.5
03/12 Neutral Miami -1.5 L by 5 -6.5
03/19 Neutral S Florida -2.5 W by 4 +1.5
03/21 Neutral Michigan St +5.5 L by 8 -2.5

Indiana Detailed ATS Performance

Date H/A/N Opponent Line Result +/-
11/05 Home Alabama A&M -30.0 W by 47 +17.0
11/09 Neutral Marquette -3.0 W by 23 +20.0
11/12 Home Milwaukee -25.0 W by 31 +6.0
11/16 Home Incarnate Word -28.5 W by 8 -20.5
11/20 Home Lindenwood -33.5 W by 20 -13.5
11/25 Home Kansas St -10.5 W by 17 +6.5
11/29 Home Bethune -29.5 W by 44 +14.5
12/03 Away Minnesota -8.0 L by 9 -17.0
12/06 Neutral Louisville +4.0 L by 9 -5.0
12/09 Home Penn St -14.5 W by 41 +26.5
12/13 Away Kentucky +3.5 L by 12 -8.5
12/20 Home Chicago St -38.5 W by 20 -18.5
12/22 Home Siena -21.5 W by 21 -0.5
01/04 Home Washington -9.0 W by 10 +1.0
01/07 Away Maryland -8.0 W by 18 +10.0
01/10 Home Nebraska -4.5 L by 6 -10.5
01/13 Away Michigan St +6.5 L by 21 -14.5
01/17 Home Iowa -3.5 L by 17 -20.5
01/20 Away Michigan +15.5 L by 14 +1.5
01/23 Away Rutgers -7.5 W by 23 +15.5
01/27 Home Purdue +4.5 W by 5 +9.5
01/31 Away UCLA +4.0 W by 1 +5.0
02/03 Away USC -1.5 L by 6 -7.5
02/07 Home Wisconsin -3.5 W by 1 -2.5
02/09 Home Oregon -10.5 W by 18 +7.5
02/15 Away Illinois +8.5 L by 20 -11.5
02/20 Away Purdue +11.0 L by 29 -18.0
02/24 Home Northwestern -9.5 L by 4 -13.5
03/01 Home Michigan St +2.5 L by 13 -10.5
03/04 Home Minnesota -6.5 W by 30 +23.5
03/07 Away Ohio St +3.5 L by 13 -9.5
03/11 Neutral Northwestern -6.5 L by 13 -19.5