Louisville at Pittsburgh: Head to Head

Saturday Sep 27, 2025 12:00 pm - Pittsburgh, PA
Odds: Louisville by 3, Total Points: 54

Matchup Menu: LOU @ PITT

These teams have met 2 times in the last 3 seasons (with 2026-2027 counting as one of those three). Louisville has the better record at 2-0.

Below is their head-to-head history back through the 1995 season, not just over the past three seasons.

Date	Winner	Winner H/A/N	Score	ATS Cover	O/U Result
09/27/25	Louisville	Away	34-27	Louisville -3.0	Over 54.0
11/23/24	Louisville	Home	37-9	Louisville -7.0	Under 57.0
10/14/23	Pittsburgh	Home	38-21	Pittsburgh +7.0	Over 45.0
10/22/22	Louisville	Home	24-10	Louisville -1.5	Under 55.0
09/26/20	Pittsburgh	Home	23-20	Push	Under 53.5
11/21/15	Pittsburgh	Home	45-34	Pittsburgh +1.0	Over 48.5
10/13/12	Louisville	Away	45-35	Louisville -2.5	Over 49.0
11/12/11	Pittsburgh	Away	21-14	Pittsburgh +3.0	Under 45.5
10/30/10	Pittsburgh	Home	20-3	Pittsburgh -9.5	Under 56.0
10/02/09	Pittsburgh	Away	35-10	Pittsburgh -7.0	Under 53.0
11/08/08	Pittsburgh	Home	41-7	Pittsburgh -6.0	Under 52.0
10/27/07	Louisville	Home	24-17	Pittsburgh +10.5	Under 62.0
11/25/06	Louisville	Away	48-24	Louisville -12.5	Over 58.0
11/03/05	Louisville	Home	42-20	Louisville -18.0	Under 66.5